Quantifying cancer progression with conjunctive Bayesian networks
نویسندگان
چکیده
منابع مشابه
Quantifying cancer progression with conjunctive Bayesian networks
MOTIVATION Cancer is an evolutionary process characterized by accumulating mutations. However, the precise timing and the order of genetic alterations that drive tumor progression remain enigmatic. RESULTS We present a specific probabilistic graphical model for the accumulation of mutations and their interdependencies. The Bayesian network models cancer progression by an explicit unobservable...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2009
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/btp505